Gross Hyperkeratosis of Palms and Soles, Pemphigoid and Epilepsy

Hemorrhagic vesiculobullous eruption on the palms and the soles as presentation of dyshidrosiform bullous pemphigoid

BP: bullous pemphigoid DP: dyshidrosiform pemphigoid INTRODUCTION Dyshidrosiform bullous pemphigoid (DP) is an unusual localized variant of bullous pemphigoid (BP), first described by Levine et al in 1979. It presents with a persistent and recurrent vesicobullous eruption, sometimes hemorrhagic, localized to the soles and/or palms. Since the clinical manifestations of DP are similar to those of...

Keratotic papules of palms and soles

A 40-year-old white Caucasian woman presented with a 20-year history of asymptomatic lesions on palmoplantar regions. Physical examination revealed numerous keratotic papules with crateriform holes on the palms (Figure 1) and yellow pits over the areas of soles exposed to pressure (Figure 2). Her father reported the same skin signs but he was less severely affected. The patient displayed no sys...

Painful Rashes on the Palms and Soles.

Answer: E A 72-year-old male of Caucasian descent was referred for consideration of systemic therapy after receiving a diagnosis of hepatocellular carcinoma (HCC). His past medical history was unremarkable with no comorbidities and he was not on any other medications. Computer tomography (CT) scan revealed multifocal HCC, and a biopsy of which confirmed HCC. There was no underlying cirrhosis or...

Yellow palms and soles – more than single discoloration

The aim of this comment is highlight the role played by diets rich in carotene/lycopene on the genesis of yellow-orange skin discolorations.

Tender nodules on the palms and soles after chemotherapy.